Endocrine Abstracts

Primary hyperparathyroidism (PHPT) belongs to the most common endocrine disorders. It is increasingly reported in patients without any symptoms and hypercalcemia. In the 3rd international workshop on asymptomatic PHPT (Orlando 2008) the normocalcemic PHPT was recognised as a stand-alone entity that needs more attention.Aim: The purpose of this study is to analyse data from patients with normocalcemic asymptomatic PHPT and to create an effective source da...

Primary hyperthyroidism (PHPT) is one of the diseases which are usually diagnosed in asymptomatic period nowadays. Even though considerable success was achieved, in some cases PHPT is not found out before complications were developed. A prospective study focuses on diagnostics and therapy of PHPT has been in progress at two tertiary centers of endocrinology in the Czech Republic since January 1st, 2007, with early diagnosis of PHPT being one of its aims. In a 6-year period, th...

Best of all, the primary hyperparathyroidism (PHPT) should already be disclosed in the asymptomatic stage. The authors of this contribution are participating in a longitudinal study, which is focused on several aspects of asymptomatic PHPT. The study has been in progress in the Czech Republic at the two tertiary endocrinology centers. Previously we had attempted to verify the assumption that the presence of a chronic disease results in more frequent contact of the patient with...

Aim/Introduction: Contrast-enhanced 18F-FDG PET/CT is an effective diagnostic procedure enabling a precise localization of remnants or recurrences in patients with radioiodine-negative differentiated thyroid carcinomas (DTCs). The detection of this lesions allows to cure patients without detectable distant metastases using a loco-regional surgical treatment. The aim of this study was to assess the influence of 18F-FDG PET/CT on indication of this type of ...

Differential diagnostic search for the pathogenetic causes of hirsutism and the combination of hypertension can provide very interesting results for the clinicians. The case report demonstrates a patient suffering from two hormonally active tumors – adrenal adenoma with primary aldosteronism and primary Leydig cell ovarian tumor with hyperandrogenism. The task of the authors was easier due to the perimenopausal age of the proband. Selective venous sampling was very helpfu...

Introduction: Laproscopic adrenalectomy (LA) was first described in the literature in 1992 and has become the preferred method for the removal of functioning and non-functioning tumours. More than 75% of Las are performed for endocrine causes of hypertension such as Conn’s or Cushing’s syndrome and pheochromocytoma. The majority of centers (80%) perform laparoscopic transabdominal adrenalectomy. The first LA in our institution was performed in 1998 and the procedure ...

Background and aim: Up to now, there is paucity of studies concerning health status in adults with congenital adrenal hyperplasia (CAH). We aimed to examine a group of adult CAH patients from different Czech centers.Methods: Serum lipids, glucose, blood pressure and anhtropometrics were compared in 31 males and 71 females with CAH 21-hydroxylase deficiency and in healthy population from Czech post-MONICA study (1% random population sample).<p class="...

Introduction: The aim of this study was to evaluate the plasma levels of adiponectin and tumor necrosis factor-alpha (TNF-α) in asymptomatic, nonsmoking members of families with familial combined hyperlipidemia (FCH). We investigated the association between these cytokines and selected risk factors for atherosclerosis, markers of insulin resistance and inflammation.Methods: Eighty-two members of 29 FCH families were divided into two groups: HL (prob...